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Clinical trials for liver cancer

Liver cancer (hepatocellular carcinoma) trials weigh both the tumor and underlying liver function, so eligibility often turns on liver-health measures as much as the cancer itself.

658 recruiting trials. Showing a sample.

  • recruitingNCT07315633

    An Innovative CFD-based Dosimetry and Pre-treatment Planning Platform to Support Personalized Transarterial Therapies for Liver Cancer

    Transarterial radioembolization (TARE) is a key treatment option for patients with unresectable hepatocellular carcinoma (HCC), a primary form of liver cancer. TARE is a minimally invasive therapy in which radioactive microspheres are delivered through a microcatheter near the...

    Sponsored by University Hospital, GhentFull details on ClinicalTrials.gov →
  • recruitingNANCT07628751

    A Study of Standard Of Care Versus Radio Ablation in Early Stage HCC

    This Phase II Prospective, parallel and open-label randomised control trial will investigate whether a radiotherapy technique (called SABR) can treat early stage liver cancer more effectively than current treatments which use heating probes directly inserted into the tumour or...

    Sponsored by University Health Network, TorontoFull details on ClinicalTrials.gov →
  • recruitingNCT07679061

    First-Line Nivolumab Plus Ipilimumab in Unresectable Hepatocellular Carcinoma (J-PROMISE)

    This study looks at how a combination of two medicines, nivolumab and ipilimumab, is used to treat people with advanced liver cancer that cannot be removed by surgery. The study will follow adults receiving this treatment in routine medical care in Japan to understand how safe...

    Sponsored by Bristol-Myers SquibbFull details on ClinicalTrials.gov →
  • recruitingNCT06252753

    Observational Study Protocol: LIVER-R

    Given the number of anticipated durvalumab-based treatment launches in the hepatobiliary cancer space over the next 3 years, there is a need to capture contemporary real-world data across these indications. LIVER-R is a multicountry, multicenter, observational study of patient...

  • recruitingPhase 1NCT04952272

    Intratumor CpG-ODN Injection Boosters Immune Killing Against in Situ Tumor Antigen Release for Advanced Solid Tumors

    To study the safety and clinical effects of intratumor injecting CpG-ODN and in situ release of tumor antigen by interventional ablation or drug-eluting beads to treat advanced solid tumors.

    Sponsored by Second Affiliated Hospital of Guangzhou Medical UniversityFull details on ClinicalTrials.gov →
  • recruitingNANCT05203120

    A National Phase II Study of Proton Therapy in Hepatocellular Carcinoma

    350 new cases of hepatocellular carcinoma (HCC) are diagnosed in Denmark each year, but the overall prognosis is poor with a 1-year survival rate of less than 40% and a 5-year survival rate of 10% for the entire patient group. This national phase II non-randomized single-arm ...

    Sponsored by University of AarhusFull details on ClinicalTrials.gov →
  • recruitingNANCT05375370

    Prediction of Hepatocellular Carcinoma Recurrence After Curative Treatment by Monitoring Circulating Tumor DNA

    The goal of the REMNANT study is to confirm the clinical value of detecting a new biomarker, ctDNA (circulating tumor DNA), in the follow-up of patients with operated liver cancer. In order to meet this objective, this biomarker will be measured in your blood before and after ...

    Sponsored by University Hospital, RouenFull details on ClinicalTrials.gov →
  • recruitingPhase 1NCT07369505

    Sapu003 in Advanced mTOR-sensitive Solid Tumors

    This is a phase 1b, open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics of Sapu003 in combination with Exemestane in in patients with advanced mTOR-sensitive solid tumors (HR+/HER2-negative breast cancer, renal cell carcinoma \[RCC\], neuro...

    Sponsored by SAPU NANO (US) LLCFull details on ClinicalTrials.gov →
  • recruitingNCT05866783

    Serum Glycomics as Prognostic and Diagnostic Biomarkers of Disease Recurrence in Liver Transplant Recipients With Hepatocellular Carcinoma

    Liver transplantation (LT) is the only curative option for a selection of patients with hepatocellular carcinoma (HCC) based on clinical selection criteria known as the Milan criteria. Nevertheless, 15% of these patients still show tumour recurrence after LT. In a monocentric ...

    Sponsored by University Hospital, GhentFull details on ClinicalTrials.gov →
  • recruitingNANCT07751783

    Development and Dissemination of Exercise Prescription and Intervention for Cancer Populations

    The purpose of this study is to establish a safe and systematic exercise assessment and prescription program for cancer survivors. It can be challenging for cancer patients to start exercising due to various health risks, so this study aims to create a personalized and easily ...

    Sponsored by Kaohsiung Medical University Chung-Ho Memorial HospitalFull details on ClinicalTrials.gov →

Data from ClinicalTrials.gov, retrieved 2026-08-08. These are trials worth asking your care team about, not a determination that anyone qualifies. Eligibility is decided by the trial's own doctors.

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Common questions

Is this liver cancer trial finder really free?
Yes. You describe the situation, we search ClinicalTrials.gov and show what matches. No account, no payment, no email required. Nothing you type is saved.
Does showing up here mean the patient qualifies?
No. These are trials worth asking your care team about. Every trial has detailed eligibility criteria that the trial's own doctors evaluate, and many depend on test results and treatment history that only your medical team knows in full.
How current is this list?
The trials come directly from ClinicalTrials.gov and are refreshed daily. Each result links to the full, live study record, and the finder above always runs a fresh search when you use it.
What should I do with a trial that looks promising?
Bring it to your oncologist or care team, and mention the NCT number (the ID that starts with NCT). They can tell you whether it is a genuine fit and refer you to the trial site.

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