Free tool · No account

Clinical trials for liver cancer

Liver cancer (hepatocellular carcinoma) trials weigh both the tumor and underlying liver function, so eligibility often turns on liver-health measures as much as the cancer itself.

660 recruiting trials. Showing a sample.

  • recruitingPhase 1NCT06478693

    A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC

    This is a multicenter, open-label, Phase 1, first-in-human, dose-escalation study designed to assess the safety, tolerability and define the RP2D of MT-303 alone (Module 1) and in combination with Atezo/Bev (Module 2) in participants with advanced hepatocellular carcinoma expr...

    Sponsored by Myeloid TherapeuticsFull details on ClinicalTrials.gov →
  • recruitingNCT07365930

    NIS on the Benefits of TIPS in Patients With HCC Receiving Atezo+Bev in 1st-Line Therapy

    The NISTIPS TRITICC-4 study is a prospective, multicentre, non-interventional cohort study to analyze the effectiveness of transjugular intrahepatic portosystemic shunting (TIPS) in patients with Hepatocellular carcinoma (HCC) receiving atezolizumab plus bevacizumab as first-l...

    Sponsored by Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestFull details on ClinicalTrials.gov →
  • recruitingNCT04792463

    Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

    This research will have a significant impact on the overall management of those cancer patients and their family members who are at risk for hereditary cancer due to germline inactivation of BAP1. Our study will ultimately facilitate the development of novel screening, prevent...

    Sponsored by Mohamed Abdel-RahmanFull details on ClinicalTrials.gov →
  • recruitingPhase 3NCT05482516

    Evaluating Novel Therapies in ctDNA Positive GI Cancers

    This study is a non-randomized, open-label, multi-cohort, multi-site, pilot feasibility therapeutic trial. The study will enroll 20 patients across 4 cohorts (CRC, gastric, PDAC, and HCC/intra-hepatic-/extra-hepatic-, gall bladder adenocarcinomas) diagnosed with histologically...

    Sponsored by Georgetown UniversityFull details on ClinicalTrials.gov →
  • recruitingPhase 3NCT06492395

    Lenvatinib Plus DEB-TACE and HAIC vs. Lenvatinib Plus DEB-TACE for Large HCC With PVTT

    This study is conducted to evaluate the efficacy and safety of lenvatinib plus transarterial chemoembolization (TACE) with drug-eluting beads (DEB-TACE) and hepatic artery infusion chemotherapy (HAIC) with FOLFOX regemen (Len+DEB-TACE+HAIC) versus lenvatinib plus DEB-TACE (Len...

    Sponsored by Second Affiliated Hospital of Guangzhou Medical UniversityFull details on ClinicalTrials.gov →
  • recruitingPhase 3NCT05201404

    Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis

    This is a clinical trial in patients with advanced hepatocellular carcinoma (HCC) and Child-Pugh Class B7 (CPB7) cirrhosis whose disease has progressed on at least 1st-line therapy. The trial will evaluate the efficacy and safety of namodenoson as compared to placebo.

    Sponsored by Can-Fite BioPharmaFull details on ClinicalTrials.gov →
  • recruitingNANCT06990659

    Outpatient Versus Inpatient Care Pathway for Intra-arterial Treatment of Primary Liver Cancer (CHOC)

    Randomized multicentre trial comparing two care organisations (ambulatory vs conventional inpatient) for patients undergoing transarterial chemoembolization (TACE) or radioembolization (TARE) for primary liver cancer (Hepato Cellular Carcinoma (HCC) or intrahepatic cholangioca...

    Sponsored by University Hospital, AngersFull details on ClinicalTrials.gov →
  • recruitingPhase 2NCT06762782

    Clinical Study on the Effectiveness and Safety of Lenvatinib As Adjuvant Treatment for Patients with High-risk Recurrence of Hepatocellular Carcinoma After Surgery

    This study is a prospective, randomized, controlled, open, phase II, multicenter clinical study, which aims to evaluate the efficacy and safety of lenvatinib for adjuvant treatment of high-risk recurrent liver cancer after radical surgery. This study is divided into 3 stages:...

    Sponsored by The First Affiliated Hospital with Nanjing Medical UniversityFull details on ClinicalTrials.gov →
  • recruitingEARLY_Phase 1NCT06383520

    Study on the Clinical Application Value of PET Imaging Targeting GPC3 in Hepatocellular Carcinoma

    This is a diagnostic study. Patients were recruited from patients with clinically suspected or confirmed hepatocellular carcinoma and healthy volunteers were recruited for PET/or PET/CT imaging targeting a GPC3-specific probe (in the case of 68Ga-NOTA-aGPC3-scFv) , to observe ...

    Sponsored by Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyFull details on ClinicalTrials.gov →
  • recruitingPhase 1NCT06461624

    Clinical Trial of Autologous GPC3 CAR-T Cells (CBG166) Therapy for Advanced Hepatocellular Carcinoma

    A phase I clinical study of 4th generation chimeric antigen receptor T Cells targeting glypican-3 ( CAR-GPC3 T Cells) in patients with advanced hepatocellular carcinoma.

    Sponsored by Zhejiang UniversityFull details on ClinicalTrials.gov →

Data from ClinicalTrials.gov, retrieved 2026-08-27. These are trials worth asking your care team about, not a determination that anyone qualifies. Eligibility is decided by the trial's own doctors.

Refine for your situation

Add whatever you know: an age, a city, a mutation from a pathology report. We'll narrow the list to trials that fit. Describe it in your own words.

Whatever you have: the diagnosis, a mutation if you know it, age, where you live.

Trials for other conditions

What we will never do with your records

This generator runs without an account, and KeptWell itself makes the same promises to every family, regardless of plan or price.

We won't sell your data.
Not to advertisers, not to data brokers, not to insurers, not to pharma, not to anyone, in any form, ever.
We won't train AI models on your records.
KeptWell does not opt in to model training. OpenAI and Anthropic do not use API inputs or outputs to train their models by default.
We won't lock you in.
You can export everything in your circle as a ZIP at any time. Cancellation is one click.

Read the full data practices →

Common questions

Is this liver cancer trial finder really free?
Yes. You describe the situation, we search ClinicalTrials.gov and show what matches. No account, no payment, no email required. Nothing you type is saved.
Does showing up here mean the patient qualifies?
No. These are trials worth asking your care team about. Every trial has detailed eligibility criteria that the trial's own doctors evaluate, and many depend on test results and treatment history that only your medical team knows in full.
How current is this list?
The trials come directly from ClinicalTrials.gov and are refreshed daily. Each result links to the full, live study record, and the finder above always runs a fresh search when you use it.
What should I do with a trial that looks promising?
Bring it to your oncologist or care team, and mention the NCT number (the ID that starts with NCT). They can tell you whether it is a genuine fit and refer you to the trial site.

Found trials worth discussing? Keep them next to the records.

The next step is a conversation with the care team, and that goes better when the scans, labs, and trial details live in one place everyone in the family can see. That's what KeptWell is: the binder, but it understands what's inside.

Get started

We'll email you a secure sign-in link. It works whether you're new here or already have an account.