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Clinical trials for melanoma

Melanoma has been a proving ground for immunotherapy, and many trials build on that. Some are limited to tumors with a BRAF mutation, so that detail is worth including if you have it.

474 recruiting trials. Showing a sample.

  • recruitingPhase 3NCT06519266

    PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases

    Uveal melanoma is the most common primary intraocular malignancy in adults. Despite successful control of the primary tumor, metastatic disease will develop in approximately 35%-50% of the patients within 10 years. The liver is the most common site for metastases, and about 50...

    Sponsored by Vastra Gotaland RegionFull details on ClinicalTrials.gov →
  • recruitingNCT04095195

    Registry of Subjects at Risk of Pancreatic Cancer

    IRFARPC is a multicenter national registry designed to study the diagnosis and predisposing factors of subjects with an inherited increased risk for pancreatic cancer.

    Sponsored by Associazione Italiana per lo Studio del PancreasFull details on ClinicalTrials.gov →
  • recruitingPhase 1, Phase 2NCT04895709

    A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

    The purpose of this study is to assess the safety, tolerability, and recommended dose(s) of BMS-986340 as monotherapy and in combination with nivolumab, docetaxel, or Pumitamig in participants with advanced solid tumors. This study is a first-in-human (FIH) study of BMS-986340...

    Sponsored by Bristol-Myers SquibbFull details on ClinicalTrials.gov →
  • recruitingPhase 1, Phase 2NCT05269381

    Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

    This phase I/II trial tests the safety and tolerability of an experimental personalized vaccine when given by itself and with pembrolizumab in treating patients with solid tumor cancers that have spread to other places in the body (advanced). The experimental vaccine is design...

  • recruitingPhase 1, Phase 2NCT00722228

    Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors

    This study is based on the finding that tumor cells that are grown in the laboratory can be modified in such a way that, when injected to the patient, they will stimulate his/her immune response. This approach will be evaluated in patients with melanoma and colorectal, gastric...

    Sponsored by Hadassah Medical OrganizationFull details on ClinicalTrials.gov →
  • recruitingNCT03054584

    Genetic Basis of Melanocytic Nevi

    The objective of this protocol is to further elucidate the genetic mutations that drive melanocytic nevi (benign melanocytic neoplasms, moles). This will be performed by whole genome, whole exome, or targeted sequencing of de-identified specimens. Herein, the investigators pl...

    Sponsored by University of California, DavisFull details on ClinicalTrials.gov →
  • recruitingPhase 2NCT06560905

    Preoperative Planning With PSMA-PET in Melanoma Surgery Trial

    This is a non-randomised, single-centre Phase 2 study, investigating whether the diagnostic biomarker, prostate-specific membrane antigen (PSMA), can detect melanoma metastases using PSMA PET/ CT.

    Sponsored by Royal Marsden NHS Foundation TrustFull details on ClinicalTrials.gov →
  • recruitingNANCT05253872

    The MELAcare Study: A New Method for Surveillance of Melanoma Patients

    The aim of this study is to evaluate a new method of follow-up for patients with low and intermediate risk (stages IA-IIA) melanoma. The investigators will compare different tools for patient support and education combined with clinician supported skin self-examination (SSE) t...

    Sponsored by Herlev and Gentofte HospitalFull details on ClinicalTrials.gov →
  • recruitingPhase 1, Phase 2NCT07070518

    Study of GV20-0251 in Participants With Solid Tumor Malignancies

    This is a Phase 1 and Phase 2 study of GV20-0251 being developed for the treatment of participants with advanced solid tumors, who are refractory to approved therapies or other standard of care.

    Sponsored by GV20 TherapeuticsFull details on ClinicalTrials.gov →
  • recruitingNCT05180942

    Statins and prOgression of Coronary atheRosclerosis in melanomA Patients Treated With chEckpoint inhibitorS

    This study is a prospective observational study evaluating the natural history of coronary plaque burden in participants with melanoma treated with ICI. The study will be conducted at various sites across Australia.

    Sponsored by Monash UniversityFull details on ClinicalTrials.gov →

Data from ClinicalTrials.gov, retrieved 2026-07-13. These are trials worth asking your care team about, not a determination that anyone qualifies. Eligibility is decided by the trial's own doctors.

Refine for your situation

Add whatever you know: an age, a city, a mutation from a pathology report. We'll narrow the list to trials that fit. Describe it in your own words.

Whatever you have: the diagnosis, a mutation if you know it, age, where you live.

Trials for other conditions

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Common questions

Is this melanoma trial finder really free?
Yes. You describe the situation, we search ClinicalTrials.gov and show what matches. No account, no payment, no email required. Nothing you type is saved.
Does showing up here mean the patient qualifies?
No. These are trials worth asking your care team about. Every trial has detailed eligibility criteria that the trial's own doctors evaluate, and many depend on test results and treatment history that only your medical team knows in full.
How current is this list?
The trials come directly from ClinicalTrials.gov and are refreshed daily. Each result links to the full, live study record, and the finder above always runs a fresh search when you use it.
What should I do with a trial that looks promising?
Bring it to your oncologist or care team, and mention the NCT number (the ID that starts with NCT). They can tell you whether it is a genuine fit and refer you to the trial site.

Found trials worth discussing? Keep them next to the records.

The next step is a conversation with the care team, and that goes better when the scans, labs, and trial details live in one place everyone in the family can see. That's what KeptWell is: the binder, but it understands what's inside.

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